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824982-41-4 (A 784168)

1

Identification

A 784168 A 784168
Name A 784168
Formula C19H15F6N3O3S
MW 479.4
CAS No. 824982-41-4
EINECS
Smiles FC(C1=CC=CN=C1N2CCC(C(NC3=CC=C(S(=O)(C(F)(F)F)=O)C=C3)=O)=CC2)(F)F
Synonyms 3'-(trifluoromethyl)-N-(4-((trifluoromethyl)sulfonyl)phenyl)-3,6-dihydro-2H-[1,2'-bipyridine]-4-carboxamide
InChI InChI=1S/C19H15F6N3O3S/c20-18(21,22)15-2-1-9-26-16(15)28-10-7-12(8-11-28)17(29)27-13-3-5-14(6-4-13)32(30,31)19(23,24)25/h1-7,9H,8,10-11H2,(H,27,29)
2

Introduction

Background Information

Potent TRPV1 antagonist (IC<sub>50</sub> = 25 nM for inhibition of TRPV1 activation by 50 nM capsaicin). Displays no activity against a range of receptors, including TRPA1, GABA, opioid, and purinergic receptors. ......by Tocris Bioscience Inc.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance: EBNumber:EB000124052

Storage condition

Store at RT by Tocris Bioscience Inc.

Solubility

Soluble to 100 mM in DMSO and to 50 mM in ethanol by Tocris Bioscience Inc.
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Mechanism and Indication

Signaling Pathways
Target
Research Area
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
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Safety Data of A 784168

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Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
Tocris Bioscience Inc. USA
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Related Products

Other Forms of 824982-41-4

Name CAS No Formula MW

Recommended Compounds in

Name CAS No Formula MW

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

12

References

Protocol Reference

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More Information

A 784168

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