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Phlorizin

(CAS: 60-81-1)

Suppliers of Phlorizin

Company Name Email Tel Country
Affix Scientific [email protected] +1-510-936-6647 USA

Fax: Purity: ≥98% Brand:

Price and Availability: USD400/5g (In stock) USD550/10g (In stock)
Quality Control & MSDS Files: CoA MSDS

Aktin Chemicals Inc [email protected],[email protected] +86 (28) 8515-9085 China

Fax: +86 (28) 8515-2372Purity: Brand:

Ankang Zhongke Maidisen Natural Pharmaceutical Co., Ltd. [email protected] +86 (29) 8223-6926 China

Fax: +86 (29) 8225-5087Purity: Brand:

BioBioPha Co., Ltd. [email protected] +86 (871) 6521-7109 China

Fax: +86 (871) 6521-5563Purity: Brand:

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: >98% Brand:

Chengdu Biopurify Phytochemicals Ltd. [email protected],[email protected] +86 (28) 8263-3860 / 8263-3987 China

Fax: +86 (28) 8263-3165Purity: Brand:

Fraken Biochem Co., Ltd. [email protected] +86 (532) 8389-9718 China

Fax: +86 (532) 8362-3236Purity: Brand:

Hangzhou Skyherb Technologies Co., Ltd. [email protected] +86 (571) 8805-3319 China

Fax: +86 (571) 8805-4060Purity: Brand:

Indofine Chemical Company, Inc. [email protected] +1 (888) 463-6346 USA

Fax: +1 (908) 359-1179Purity: Brand:

Ivy Fine Chemicals [email protected] +1 (856) 465-8550 USA

Fax: +1 (856) 616-1161Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: >98% Brand:

Price and Availability: USD50/1g (In stock) USD190/5g (In stock)
Quality Control & MSDS Files: HNMR LCMS MSDS

Nanning Weikang Pharmaceutical Technology Co., Ltd. [email protected] +86 (771) 451-6110 China

Fax: +86 (771) 451-6130Purity: Brand:

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: >98% Brand:

Price and Availability: USD40/500mg (In stock) USD50/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HNMR HPLC HPLC HNMR HPLC

Shaanxi Green Bio-Engineering Co., Ltd. [email protected],[email protected] +86 (29) 8621-5910 / 8621-5920 / 8621-5930 China

Fax: +86 (29) 8621-5580Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: >98% Brand:

Price and Availability: USD40/1g (Get quote) USD120/5g (Get quote)

Sino-Future Bio-Tech Co., Ltd. [email protected] +86 (29) 8318-2005 China

Fax: Purity: Brand:

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD23/20mg () USD45/50mg () USD110/250mg () USD168/500mg ()

Tocris Bioscience Inc. [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: #99 % Brand: Tocris

Wilshire Technologies [email protected] +1 (609) 683-1117 USA

Fax: Purity: Brand:

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Background Information of Phlorizin

Phlorizin, a natural product and dietary constituent found in a number of fruit trees, is a 2'-glucoside of phloretin, Phlorizin is a competitive and classic inhibitor of hSGLT1(Ki=300 nM) and hSGLT2(Ki= 39 uM).

Solubility of Phlorizin

Solubility Sources
DMSO 87 mg/ml; Water <1 mg/ml MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 87 mg/mL warming (199.35 mM); Ethanol9 mg/mL warming (20.62 mM); Water<1 mg/mL (<1 mM) Selleck Chemicals LLC
Soluble to 100 mM in DMSO and to 100 mM in ethanol Tocris Bioscience Inc.

Storage Condition of Phlorizin

Storage Condition Sources
Up to one week at 4°C or six months at -20°C. Affix Scientific
Store at -20&deg;C Tocris Bioscience Inc.

MSDS Information

MSDS Sources
Affix Scientific
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[CoA] Affix Scientific
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Membrane Transporter/Ion Channel
Target SGLT
Research Area Metabolic Disease
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Phlorizin - Not Found
Phlorizin - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
436.41 C21H24O10 60-81-1 1-(2-(beta-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)-propan-1-on; 1-(2,4-dihydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one

Structure Information of Phlorizin

Smiles O=C(CCC1=CC=C(O)C=C1)C(C(O)=CC(O)=C2)=C2O[[email protected]@H]3O[[email protected]](CO)[[email protected]@H](O)[[email protected]](O)[[email protected]]3O
InChI InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1

Related Products

Other Form Products of Phlorizin

Name CAS Formula Suppliers
Phlorizin dihydrate 7061-54-3 C21H28O12 5

Recommended Products in Same Target

Name CAS Formula Suppliers
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Phloretin 60-82-2 C15H14O5 20
LX-4211 1018899-04-1 C21H25ClO5S 8
TOFOGLIFLOZIN 1201913-82-7 C22H28O7 4
PF-04971729 1210344-57-2 C22H25ClO7 3
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CSG 452 903565-83-3 C22H26O6 4
Ipragliflozin 761423-87-4 C21H21FO5S 9
Dapagliflozin 461432-26-8 C21H25ClO6 16
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Safety Data of Phlorizin

Hazard Symbols:Xi Risk Statements:36/37/38 Safety Statements:26-36
Transport Information: HS Code: RTECS:UC2080000
WGK Germany:3

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:113-114 °C(lit.)
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:7327
BRN: Refractive Index: -54 ° (C=3.2, 95% EtOH)
Vapour: EINECS:200-487-1
Optical Rotation: alpha:

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